2026
- BeNeBio: Dose reduction of the new generation biologics (IL17 and IL23 inhibitors) in psoriasis: A pragmatic, multi-centre, randomised, controlled, non-inferiority study (BeNeFIT18562)
- BENEFICIAL: A Multicentric, Randomised Controlled Clinical Trial To Study The Impact Of Bedside Model-Informed Precision Dosing Of Vancomycin In Critically Ill Children (KCE-181128)
- UNLOCK: Nutrition and Locomotoric rehabilitation in Long Covid (LCOV-211306)
2025
- ARON: Impact of clinical guidance & point-of-care CRP in children (KCE-181137)
- C-EASIE: Early administration of Vitamin C in patients with sepsis or septic shock in emergency departments: a multicentre, double blinded, randomized controlled trial (KCE-191237)
- CovCOG: Immediate and long term cognitive and quality of life improvement after cognitive versus emotion management psychoeducation programs: a randomised trial in covid patients with neuropsychological difficulties (LCOV21-1303)
- DUET: Azole-echinocandin combination therapy for invasive aspergillosis. A randomized pragmatic superiority trial (BeNeFIT18558)
- PuRe-COVID: Pulmonary rehabilitation for Long COVID (LCOV21-1294)
2024
- BLING III: A phase III randomised controlled trial of continuous beta-lactam infusion compared with intermittent beta-lactam dosing in critically ill patients (KCE-17005)
- CareRA 2020: COBRA-Slim with or without fast access to TNF blockade for remission induction in early rheumatoid arthritis (RA) (KCE-16002)
- GonoScreen: Efficacy of screening STIs in MSM (KCE-181133)
- IMCOVAS: Assessment of the immunogenicity and safety of marketed vaccines for COVID-19 after regular schedule and adapted vaccine schedules and routes: Comirnaty® (Pfizer), Covid-19 vaccine Moderna® (Moderna) and Vaxzevria® (AstraZeneca) (COV201288)
- PRECISE: The impact of high vs standard enteral protein provision on functional recovery following Intensive Care admission: a triple blind randomized controlled trial in mechanically ventilated, critically ill patients (BeNeFIT18574)
2023
- BeNeDuctus: Multi-center, randomized non-inferiority trial of early treatment versus expectative management of patent ductus arteriosus in preterm infants (KCE-16013)
- CONFIDENT: A multicentre randomized trial to assess the efficacy of CONvalescent plasma therapy in patients with Invasive COVID-19 and acute respiratory failure treated with mechanical ventilation (COV201004)
- SAFEBOOSC III: A pragmatic, open label, multinational randomized phase III clinical trial evaluating treatment based on near-infrared spectroscopy monitoring versus treatment as usual in premature infants (KCE-181144)
2022
- ADVOR: A multi-center, randomized, double-blind, phase IV clinical trial on the diuretic effects of Acetazolamide (Diamox ®) in patients with Decompensated heart failure and Volume OveRload (KCE-17001)
- Big Bird: The effectiveness of a blended care program for the discontinuation of benzodiazepines use for sleeping problems in primary care: a clustered randomized trial (KCE-17016)
- DOMINO: Diet Or Medication in Irritable bowel syndrome (KCE-16001)
2021
- COV-AID: A prospective, randomized interventional study to assess the safety and efficacy of interleukin-6 and interleukin-1 pathway blockade in COVID-19 patients with acute hypoxic respiratory failure and systemic cytokine release syndrome (COV201002)
- DAWN-Plasma: Donated antibodies working against nCoV (COV201003)
- DisCoVeRy: Multi-centre, adaptive, randomized trial of the safety and efficacy of treatments of COVID-19 in hospitalized adults (COV201001)
- OptiMEDs: OptiMEDs intervention for multidisciplinary medication review in nursing homes to evaluate the appropriateness of prescribing – a pilot study (KCE-17008)
2020
- ELMO: The effect of evidence-based decision support for ordering laboratory tests in family practice: a cluster randomised trial (KCE-16011)
- Pressure Ulcer: A medical device trial to evaluate the use of a silicone adhesive multilayer foam dressing as prevention for pressure ulcer development in hospitalised patients (KCE16012)
- VINCA: Comparison of the impact of two routes of vincristine administration on vincristine-induced neuropathy in children treated for cancer (KCE-16015)
