Repetitive transcranial magnetic stimulation for treatment- resistant major depression: effectiveness and safety
- Original publication: EUnetHTA Joint Action 3 WP4. Repetitive transcranial magnetic stimulation for Treatment-resistant major depression. Project ID: WP4-ACB-CA-5. Version 4, 30 March 2017. Available from: http://www.eunethta.eu/outputs/ca-ja3-wp4-repetitive-transcranial-magnetic-stimulationtreatment-resistant-major-depression.
- This KCE has read for you was edited by Nancy Thiry, Sabine Stordeur and Chris De Laet
- Published on 31 October 2017
KEY MESSAGES OF THE ORIGINAL PUBLICATION
- Repetitive transcranial magnetic stimulation (rTMS) is generally safe and well-tolerated
- Compared with sham intervention, rTMS has a small short-term effect for improving depression (< 6 months; very low to low quality of evidence). This effect cannot be assessed in the long-term (follow-up data limited to 1-6 months) .
- Insufficient evidence hampers to prove if rTMS is as effective and safe as electro-convulsive therapy (ECT)
KCE has read for you synthesises a recently published high-quality systematic review or health technology assessment with relevance for the Belgian health system.
The original publication was appraised and contextualised by KCE researchers. KCE has read for you is not based on original research conducted by KCE.
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This document includes
- Key findings of the publication under evaluation
- A contextualisation within the Belgian healthcare system
- Detailed descriptions
Trustworthy original publication
The methodological quality of the systematic review was assessed with the AMSTAR tool.