EFFECTIVENESS AND SAFETY OF CARBON ION BEAM RADIOTHERAPY (CIRT)
- Original publication: Goetz, G, Mitic, M. Carbon ion beam radiotherapy (CIRT) for can-cer treatment: a systematic review of effectiveness and safety for 12 oncologic indicati-ons. HTA Project Report No. 101; 2018. Vienna: Ludwig Boltzmann Institute for Health Technology Assessment.
- This KCE has read for you was prepared by Lorena San Miguel and Frank Hulstaert
- Published on 4 February 2019
KEY MESSAGES FROM THE ORIGNAL PUBLICATION
- Only 1 randomised, open label, pilot study (high risk of bias) focusing on safety and 3 case-control studies (moderate risk of bias).
- Overall, 54 indications were studied. No evidence was found for 41 indications, and insufficient scientific evidence was found for the remaining 13.
- The technique should, to this date, be considered as “experimental”.
- More research (RCTs) is needed to reach clear conclusions on the clinical value of CIRT for cancer therapy.
KCE has read for you synthesises a recently published high-quality systematic review or health technology assessment with relevance for the Belgian health system.
The original publication was appraised and contextualised by KCE researchers. KCE has read for you is not based on original research conducted by KCE.
More details on methodology can be found on the KCE website.
This document includes
- Key findings of the publication under evaluation
- A contextualisation within the Belgian healthcare system
- Detailed descriptions
Trustworthy original publication
The methodological quality of the systematic review was assessed with the AMSTAR tool.