All reports
All KCE reports are available in Dutch, French and English under several formats. Form and language of the reports
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Polyvalent immunoglobulins – Part 2: Use in Belgium
KCE Reports 336 (2020)
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Polyvalent immunoglobulins – Part 1: A rapid review
KCE Reports 327 (2019)
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The use of statins in the primary prevention of cardiovascular disease: an online tool for shared-decision making
KCE Reports 324 (2019)
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Bariatric surgery: an HTA report on the efficacy, safety and cost-effectiveness
KCE Reports 316 (2019)
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Cost-effectiveness analysis of HPV vaccination of boys in Belgium
KCE Reports 308 (2019) The vaccine for the human papilloma virus (HPV) which causes cervical cancer was introduced about ten years ago in Belgium, but only girls benefit from it. However, it is now established that this same virus is also involved in other cancers, including throat cancer. The recommendations have thus been reviewed and here, as in most western countries, it is now recommended to vaccinate boys too.
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Proton beam therapy in adults
KCE Reports 307 (2019) Proton therapy is a radiation therapy technique which allows large doses of radiation to be delivered to cancerous tumours without (excessively) “overflowing” to adjacent tissues. There has been much talk of this technique in recent years, since two projects by proton therapy centres are ongoing in Belgium, one in Louvain and the other in Charleroi.
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Statins for the primary prevention of cardiovascular events
KCE Reports 306 (2019) A healthy lifestyle remains the most effective way of avoiding cardiovascular diseases and their consequences. Yet since 2002, the annual number of people who use cholesterol-lowering drugs from the statin family increased from 400,000 to 1,500,000. Currently, 25% of the population aged 40 and above take these drugs. Despite decreases in price due to the fact that all statins now exist in generic form, their total cost still stands at 160 million euros annually.
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MammaPrint® test for personalised management of adjuvant chemotherapy decisions in early breast cancer
KCE Report 298 (2018) Breast cancer is the most commonly diagnosed cancer in women in Belgium and throughout the world. Provided this cancer is in the early stage, treatment is essentially locoregional, that is, via surgery alone or combined with radiation therapy. In theory, this treatment is enough to eradicate the tumour since it is still limited. However, it is known that about 30% of patients treated in this way are at risk of developing remote metastases, because metastatic cancerous cells are already present but undetectable at the time of diagnosis.
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Responsible use of high-risk medical devices: the example of 3D printed medical devices
KCE Reports 297 (2018) 3D printing is generating increased interest in the medical sector, namely in orthopaedics and dentistry, but there is no evidence that 3D-printed implants are as effective or safe as “classical” products. Yet they can currently be used without restrictions by doctors, even when they are “at high risk” (that is, more often than not, implantable).
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Static automated external defibrillators for opportunistic use by bystanders
KCE Reports 294 (2017)
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Bevacizumab in the treatment of ovarian cancer
KCE Reports 285 (2017)
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Anticoagulants in non-valvular atrial fibrillation
KCE Reports 279 (2016)
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Economic evaluation of novel direct acting antiviral (DAA) treatment strategies for chronic hepatitis C
KCE Reports 276 (2016)
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Elective caesarean section in low-risk women at term: consequences for mother and offspring
KCE Reports 275 (2016)
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Use of pneumococcal vaccines in the elderly: an economic evaluation
KCE Reports 274 (2016) Supplementary material pdf fileR274_Supplementary-file_Univariate-sensitivity-analyses (13.95 MB) pdf fileR274_Supplementary-file_Sensitivity-analyses_PPV23-price (1.1 MB) pdf fileR274_Supplementary-file_Multivariate-sensitivity-analyses_Net-benefit-Box-plots (1.16 MB) pdf fileR274_Supplementary-file_Multivariate-sensitivity-analyses_CEAFs-and-CE-planes (58.74 MB) The results are also available in a searchable spreadsheet-database format for all scenario and sensitivity analyses.
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Left ventricular assist devices in the treatment of end-stage heart failure
KCE Reports 264 (2016)
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The role of biomarkers in ruling out cerebral lesions in mild cranial trauma
KCE Reports 261 (2016)
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Percutaneous Vertebroplasty and Balloon Kyphoplasty
KCE Reports 255 (2015)
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Cervical and lumbar total disc replacements
KCE Reports 254 (2015)
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Autologous breast reconstruction techniques after mammary resection: time measurements for a potential reevaluation of the surgeon fee
KCE Reports 251 (2015)