KCE-181137: Auswirkungen von klinischer Beratung und Point-of-Care-CRP bei Kindern: das ARON-Projekt

Zusammenfassung (Niederländisch oder Französisch oder Englisch)

 

Trial Description
Title Impact of a diagnostic algorithm including clinically guided point-of-care C-reactive protein testing and safety netting advice on antibiotic prescribing rate and further management of acutely ill children presenting to ambulatory care: multicentre, cluster-randomized, parallel group pragmatic trial

Participants (P)

Children aged 6 months to 12 years of age with an acute illness episode presenting to in-hours general practice or out-of-hospital community paediatrics offices

Intervention (I)

Diagnostic algorithm including a point of care CRP test

Control (C)

Diagnosis and Treatment/Management as per usual care

Outcome (O)

Antibiotic prescribing rate at index consultation

Trial Design

Multicentre, cluster-randomized, parallel group pragmatic trial

Sample Size

122 GPs including 6111 children

Trial duration

33 months from FPI to CSR

Budget

€2,980,000

Status

Open

 

Trial team

Sponsor

UZ Leuven

Chief Investigator

Prof Dr Jan Y Verbakel

Participating Investigators

Academic centres for general practice of KU Leuven, U Liege, U Gent, VUB, U Antwerp, UC Louvain

Lead Dutch speaking GPs

Prof Dr An De Sutter

Lead French speaking GPs

Prof Dr Marc Vanmeerbeek

External partner

Abbott Rapid Diagnostics BV

Dokumente
Protocol  
Report

Q2/2023

Publication

 

REFERENZEN
FINANZIERUNGSSCHEMA

2018 Investigator led