KCE-181137: Auswirkungen von klinischer Beratung und Point-of-Care-CRP bei Kindern: das ARON-Projekt
Zusammenfassung (Niederländisch oder Französisch oder Englisch)
Trial Description
| Title | Impact of a diagnostic algorithm including clinically guided point-of-care C-reactive protein testing and safety netting advice on antibiotic prescribing rate and further management of acutely ill children presenting to ambulatory care: multicentre, cluster-randomized, parallel group pragmatic trial |
|
Participants (P) |
Children aged 6 months to 12 years of age with an acute illness episode presenting to in-hours general practice or out-of-hospital community paediatrics offices |
|
Intervention (I) |
Diagnostic algorithm including a point of care CRP test |
|
Control (C) |
Diagnosis and Treatment/Management as per usual care |
|
Outcome (O) |
Antibiotic prescribing rate at index consultation |
|
Trial Design |
Multicentre, cluster-randomized, parallel group pragmatic trial |
|
Sample Size |
122 GPs including 6111 children |
|
Trial duration |
33 months from FPI to CSR |
|
Budget |
€2,980,000 |
|
Status |
Open |
Trial team
|
Sponsor |
UZ Leuven |
|
Chief Investigator |
Prof Dr Jan Y Verbakel |
|
Participating Investigators |
Academic centres for general practice of KU Leuven, U Liege, U Gent, VUB, U Antwerp, UC Louvain |
|
Lead Dutch speaking GPs |
Prof Dr An De Sutter |
|
Lead French speaking GPs |
Prof Dr Marc Vanmeerbeek |
|
External partner |
Abbott Rapid Diagnostics BV |
REFERENZEN
Clinicaltrials.gov: NCT04470518
